Monday, Apr. 17, 1939

Sulfanilamide for TB

Newest member of the rapidly growing sulfanilamide family is a little number called N^1 dodecanoylsulfanilamide. It is a combination of the parent drug with part of a fat. Last week at the Baltimore meeting of the American Chemical Society Dr. Moses Leverock Crossley, director of Calco Chemical Co. at Bound Brook, N. J., announced that the new drug had successfully checked the growth of tuberculosis in guinea pigs.

Animals inoculated first with human tuberculosis germs and then with the new drug developed only mild infections at the site of the injections. All those inoculated with germs but not the drug died of tuberculosis. The sulfanilamide compound, said Dr. Crossley, does not cure advanced tuberculosis, nor do the animal tests "permit any conclusion . . . as to the [drug's] efficacy in the treatment of this disease in man."

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